Autoimmune flares don’t happen ‘out of the blue’, even when it feels like it. Epigenetics can help explain why. Think of it as the way your environment and experiences like stress, infections, sleep, hormones, diet, even medications can switch certain immune genes on or off, without changing your DNA itself. In RA, these switches can turn up inflammation, making joints suddenly hurt, swell, or stiffen.
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Will Gregory, a consultant physiotherapist and vice-president of British Rheumatology Society, is an expert clinician in the world of rheumatology. He talks about the importance of keeping physically active when you have an inflammatory condition.
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